Patent ReferencesHigh performance microcapillary gel electrophoresis Velocity modulated capillary electrophoresis analysis system Fractionation and sample loading by cassette in capillary electrophoresis Process for preparation of electrophoresis Flow-rate-controlled surface-charge coating for capillary electrophoresis Patent #: 5015350 InventorsAssigneeApplicationNo. 525532 filed on 05/18/1990US Classes:204/453, With injection204/455, Using gel-filled capillary204/458, Plural rapid changes in direction of electric field (at least 1,000 times total and at more than 1/sec) (e.g., pulsed field, etc.)204/604, With injector204/605, Gel filled204/609Plural rapid changes in direction of electric field (at least 1,000 times total and at more than 1/sec) (e.g., pulsed field, etc.)ExaminersPrimary: Niebling, John F.Assistant: Koestner, Caroline Attorney, Agent or FirmInternational ClassesC25B 001/00C25B 007/00 B01D 061/42 AbstractApparatus and method for conducting electrophoresis in a capillary tube under the influence of a pulsed electric field. Apparatus for separating and detecting molecular species of a sample in a conductive medium includes a capillary tube for containing conductive medium, means for introducing a sample into a conductive medium-filled capillary tube, means for applying a pulsed electric field across the conductive medium-filled capillary tube between its ends, and means for detecting constituent molecular species of a sample in a conductive medium-filled capillary tube as they traverse the tube. A method for separating and detecting molecular species of a sample in a conductive medium includes the steps of introducing the sample into a capillary tube filled with conductive medium, applying a pulsed electric field of up to 500 volts/centimeter between the ends of the capillary, and detecting the constituent molecular species of the sample as they traverse the capillary.Other References
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