Platelet activating antagonists
Patent 5120749 Issued on June 9, 1992. Estimated Expiration Date: 
February 20, 2011. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
February 20, 2011. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesInhibition of thromboxane synthetase by 3-(1-Imidazolylalkyl) indoles 1H, 3H-pyrrolo (1,2-C) thiazole derivatives and pharmaceutical compositions Pyridylthiazolidine carboxamide derivatives and their intermediates and production of both Patent #: 4948795 InventorsApplicationNo. 658134 filed on 02/20/1991US Classes:514/337, The additional hetero ring is one of the cyclos in a polycyclo ring system546/184, Piperidines546/270.4, 1,3-thiazole ring bonded directly to the six-membered hetero ring546/277.4, Bicyclo ring system which is indole (including hydrogenated)546/278.1Having -C(=X)-, wherein X is chalcogen, bonded directly to the five- membered hetero ringExaminersPrimary: Rotman, Alan L.Assistant: Schmidt Twordzik, Barbara Attorney, Agent or FirmForeign Patent References
International ClassesC07D 403/14C07D 401/14 A61K 031/40 AbstractIndole compounds substituted at the 1- or 3 position by a (pyrid-3 yl)thiazolid-4-yl)alkyl-, (pyrid-3-yl)thiazolid-4-oyl)-, (pyrid-3-yl)dithiolan-4-yl)alkyl- or (pyrid-3-yl) dithiolan-4-ol)- group are potent inhibitors of PAF and are useful in the treatment of PAF-related disorders including anaphylactic shock, respiratory distress syndrome, acute inflammation, delayed cellular immunity, parturtition, fetal lung maturation, and cellular differentiation. |
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