U.S. patents available from 1976 to present.
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Bone growth factors and inhibitors of bone resorption for promoting bone formation

Patent 5118667 Issued on June 2, 1992. Estimated Expiration Date: Icon_subject May 3, 2011. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Bone morphogenetic protein process
Patent #: 4294753
Issued on: 10/13/1981
Inventor: Urist

Partially purified osteogenic factor and process for preparing same from demineralized bone
Patent #: 4434094
Issued on: 02/28/1984
Inventor: Seyedin ,   et al.

Bone morphogenetic protein
Patent #: 4455256
Issued on: 06/19/1984
Inventor: Urist

Bone protein purification process Patent #: 4608199
Issued on: 08/26/1986
Inventor: Caplan ,   et al.

Inventors

Assignee

Application

No. 695310 filed on 05/03/1991

US Classes:

514/12, 25 or more peptide repeating units in known peptide chain structure514/8, Glycoprotein (carbohydrate containing)514/21Produced by or extracted from animal tissue

Examiners

Primary: Schain, Howard E.
Assistant: Koh, Choon P.

Attorney, Agent or Firm

Foreign Patent References

  • 0212474 EP. 03/13/1987
  • 436469 EP. 07/13/1991
  • 8800205 WO. 01/13/1988
  • 8909787 WO. 10/13/1989
  • 8909788 WO. 10/13/1989

International Classes

A61K 037/36
A61K 037/43

Abstract

Bone growth factors are used to stimulate new bone formation when administered with agents that inhibit bone resorption. These therapeutic combinations result in an enhanced rate of bone formation with an increase in bone mass.

Other References

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