Method for production of t-butyl 3-oxobutyrates and their use
Patent 5109131 Issued on April 28, 1992. Estimated Expiration Date: 
April 28, 2009. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
April 28, 2009. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References7-Beta-[alpha-syn-methoxyimino-alpha-(2-aminothiazol-4-yl)-aceta mido]-3-[(1,2,3-thiadiazol-5-ylthio)methyl]-3-cephem-4-carboxylic acid and C1 -C6 alkyl derivatives thereof Patent #: 4399132 InventorsAssigneeApplicationNo. 295516 filed on 01/11/1989US Classes:540/227, 7-position substituent contains hetero ring540/222, Additional hetero ring containing540/2257-position substituent contains hetero ringExaminersPrimary: Rizzo, Nicholas S.Attorney, Agent or FirmForeign Patent References
International ClassC07D 501/36Foreign Application Priority Data1988-01-14 JPAbstractDisclosed are an advantageous method of industrial production of tert-butyl 3-oxobutylate, which is a useful intermediate for synthesis, characterized by reacting tert-butyl alcohol with diketene in the presence of 4-(tertiary amino) pyridine, and an industrially advantageous method of producing cephalosporin compounds or pharmaceutically acceptable salts thereof, using tert-butyl 3-oxobutylate as an intermediate.Other References
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