Stabilized Trinder reagent
Patent 5108733 Issued on April 28, 1992. Estimated Expiration Date: 
August 30, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
August 30, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References Re29498 Integral analytical element Composition for assaying hydrogen peroxide Patent #: 4716110 InventorsAssigneeApplicationNo. 575206 filed on 08/30/1990US Classes:435/14, Involving glucose or galactose435/10, Involving uric acid435/11, Involving cholesterol435/25, Involving oxidoreductase435/28, Involving peroxidase514/270, Barbituric acid or derivative (including thioanalogs)514/312, Chalcogen attached directly to the six-membered hetero ring by nonionic bonding514/376, Chalcogen bonded directly to ring carbon of the oxazole ring514/404, Divalent chalcogen or acyclic nitrogen double bonded directly to ring carbon of the diazole ring, or tautomeric equivalent514/566, Polycarboxylic acid514/709, Plural oxygens bonded directly to the same sulfur (e.g., sulfones, etc.)514/731, C of C-O- group is nuclear C of a benzene ring (e.g., phenol, phenolate, etc.)514/732Polycyclo ring system (e.g., naphthols, etc.)ExaminersPrimary: Robinson, Allen J.Assistant: Hollinden, Gary E. Attorney, Agent or FirmForeign Patent References
International ClassesG01N 033/15C12Q 001/28 C12Q 001/62 Foreign Application Priority Data1989-08-31 ITAbstractSpontaneous aspecific coloration in so-called Trinder reagents which can alter subsequent colorimetric determinations is inhibited by adding compounds of the chelating agent class to the solution. The resultant compositions contain a peroxidase enzyme, a phenylpyrazone derivative, a compound of phenolic or aromatic amine structure and a stabilizer. Preferred stabilizers are ethylenediaminetetraacetic acid (EDTA) and diethylenetriaminepentaacetic acid (DTPA).Other References
Field of SearchInvolving uric acidInvolving cholesterol Involving glucose or galactose Involving peroxidase Involving oxidoreductase Polycarboxylic acid Divalent chalcogen or acyclic nitrogen double bonded directly to ring carbon of the diazole ring, or tautomeric equivalent Chalcogen bonded directly to ring carbon of the oxazole ring C of C-O- group is nuclear C of a benzene ring (e.g., phenol, phenolate, etc.) Polycyclo ring system (e.g., naphthols, etc.) Plural oxygens bonded directly to the same sulfur (e.g., sulfones, etc.) Chalcogen attached directly to the six-membered hetero ring by nonionic bonding Barbituric acid or derivative (including thioanalogs) |
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