U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Biologically compatible collagenous reaction product and articles useful as medical implants produced therefrom

Patent 5104957 Issued on April 14, 1992. Estimated Expiration Date: Icon_subject February 28, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

2948706

3453222

Process for augmenting connective mammalian tissue with in situ polymerizable native collagen solution
Patent #: 3949073
Issued on: 04/06/1976
Inventor: Daniels ,   et al.

Photographic light-sensitive material
Patent #: 4021245
Issued on: 05/03/1977
Inventor: Nagatomo ,   et al.

Chemically and enzymatically modified collagen hemostatic agent
Patent #: 4215200
Issued on: 07/29/1980
Inventor: Miyata ,   et al.

Collagen soft contact lens
Patent #: 4223984
Issued on: 09/23/1980
Inventor: Miyata ,   et al.

Non-antigenic collagen and articles of manufacture
Patent #: 4233360
Issued on: 11/11/1980
Inventor: Luck ,   et al.

Collagen gel contact lens and method of preparation
Patent #: 4260228
Issued on: 04/07/1981
Inventor: Miyata

Collagen contact lens
Patent #: 4264155
Issued on: 04/28/1981
Inventor: Miyata

Natural protein polymer hydrogels
Patent #: 4264493
Issued on: 04/28/1981
Inventor: Battista

More ...

Inventors

Assignee

Application

No. 486558 filed on 02/28/1990

US Classes:

527/201, With ethylenically unsaturated reactant522/87Processes involving protein as reactant or as solid polymer; or compositions therefore

Examiners

Primary: Nutter, Nathan M.
Assistant: Mullis, Jeffrey

Attorney, Agent or Firm

Foreign Patent References

  • 1-297484 JP. 11/13/1989
  • WO83/00339 WO. 02/13/1983
  • AU87/00001 WO. 07/13/1987

International Class

C08H 001/06

Abstract

The present invention provides a biologically compatible collagenous reaction product comprising ethylenically unsaturated or polymeric substituted collagen, the monomeric substituents being essentially free of nitrogen, e.g., methacrylate styrene, polyvinyl, ethylene. The collagenous reaction product can be polymerized, e.g., by exposure to UV irradiation, chemical agents or atmospheric oxygen, and molded to form useful medical implant articles. Methods of preparation are also provided.

Other References

  • Chvapil and Krajicek, J. Surg. Research, vol. 3(7): 358, 1963
  • Dunn et al., Science, 157: 1329, 1967
  • Nishihara et al., Trans. Amer. Soc. Artif. Int. Organs, vol. XIII, pp. 243-248, 1967
  • Studies on Copolymer of Collagen and a Synthetic Polymer, Y. Shimizu et al., Biomat., Med. Dev., Art. Org., 5(1), pp. 49-66 (1977)
  • Studies on Composites of Collagen and a Synthetic Polymer, Y. Shimizu et al., Biomat., Med. Dev., Art. Org., 6(4), pp. 375-391 (1978)
  • Biomedical and Dental Applications of Polymers, Charles G. Gebelein et al., Polymer Science and Technology, vol. 14, Plenum Press, Re: Covalent Bonding of Collagen and Acrylic Polymers by Douglas R. Lloyd et al., pp. 59-84, 1980
  • Chemical Abstracts, vol. 110(17), 1989, Abstract No. 154899
  • Civerchia-Perez, L. et al., Proc. Natl. Acad. Sci. USA, 77(4): 2064-68 (1980) "SMA Resins: The Multifunctional Resins," Arco Chemical Company, General Bulleti
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