Method for determining by absorption of radiations the concentration of substances in absorbing and turbid matrices
Patent 5099123 Issued on March 24, 1992. Estimated Expiration Date: 
May 23, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
May 23, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 1758088 2721942 3463142 3489906 3638640 3926527 Non-invasive automatic glucose sensor system Ocular testing method and apparatus Method for determining bilirubin concentration from skin reflectance Transcutaneous pH measuring instrument InventorAssigneeApplicationNo. 527514 filed on 05/23/1990US Classes:250/345, Plural beam/detector pairs250/339.09, With calibration steps in measurement process250/339.12, Using sample absorption for chemical composition analysis250/343, With means to transmission-test contained fluent material356/39, BLOOD ANALYSIS600/310, Infrared, visible light, or ultraviolet radiation directed on or through body or constituent released therefrom600/316GlucoseExaminersPrimary: Fields, Carolyn E.Assistant: Beyer, James Attorney, Agent or FirmForeign Patent References
International ClassG01J 001/16Foreign Application Priority Data1990-05-23 EPAbstractA method and apparatus for non-invasively testing analytical substances in turbid matrices i.e. body fluids and tissues. In this method a sample is irradiated with a beam of electromagnetic energy at two alternating wavelenths, λ1 and λ2, at which the absorption by the background is the same but at one of which the radiation is absorbed by the analyte and at the other it is not. The apparatus comprises means which enable to control the input energy at λ1 and λ2 so that at the output from the sample the electric signals issuing after detection cancel in the absence of the analyte in the sample. When analyte is present cancellation no longer occurs and a signal proportional to the analyte concentration in the sample is produced. The apparatus is also designed for shifting the response back to zero when a calibrating known concentration of analyte is used as standard, thus providing a controllable zeroing base line.Other References
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