U.S. patents available from 1976 to present.
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Method of treating the oral cavity with dental floss containing chemotherapeutic agents

Patent 5098711 Issued on March 24, 1992. Estimated Expiration Date: Icon_subject December 20, 2009. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

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Inventors

Application

No. 452829 filed on 12/20/1989

US Classes:

424/401, Cosmetic, antiperspirant, dentifrice132/321, TOOTHPICK132/323, Having thread holder (e.g., flossing implement)424/49, DENTIFRICES (INCLUDES MOUTH WASH)433/216, Cleaning433/217.1By lining or coating

Examiners

Primary: Rose, Shep K.

Attorney, Agent or Firm

Foreign Patent References

  • 0086440 EP. 08/13/1983
  • 0335466 EP 10/13/1989
  • 2832005 DE 02/13/1979
  • 55-90555 JP 07/13/1980
  • 58-120782 JP 07/13/1983
  • 1262857 JP 10/13/1989
  • 2128133 GB. 04/13/1984

International Class

A61K 007/16

Abstract

Disclosed is a method of treating the oral cavity with a surfactant, silicone, and chemotherapeutic agent containing preparation released from dental floss to alter local microbial ecology including: plaque formation, gingivitis and S. mutans count.

Other References

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  • G. Bowden, J Canad Dent Assn, No. 2, 1984
  • G. Harrap et al., Archs Oral Biol., vol. 29, No. 2, pp. 87-91 (1984)
  • G. Harrap et al., Journal of Periodontal Research (1983) 18:634-642
  • R. Havenaar, J. Dent. Res. Feb. 1984, vol. 63, No. 2, pp. 120-123
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  • J. Mordenti et al., Journal of Pharmaceutical Sciences, vol. 71, No. 12, Dec. 1982
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  • Southard et al., Jada, vol. 108, Mar. 1984
  • Topitsoglou et al., Caries Res. 17:369-378 (1983)
  • Winter et al., Caries Res. 16:349-352 (1982)
  • Plaque: Current Approaches to Prevention and Control; JADA, vol. 109, Nov. 1984
  • Fine et al., Journal of Clinical Periodontology, 12: 660-666 (1985)
  • J. Van Houte, Reviews of Infectious Diseases, vol. 5, Supplement 4, Sep.-Oct. (1983)
  • Baker et al., J. Periodontal Res. 13: 474-485, (1978)
  • Tanzer et al., Antimicrobial Agents and Chemotherapy, vol. 15, No. 3, 408-414 (1979)
  • C. Baker, Dent. Items of Interest, 70: 921-934 (1948)
  • Keene et al., Jada, vol. 93, 328-333 (1976)
  • Lobene et al., Clinical Preventive Dentistry, vol. 4, No. 1, 5-8 (1982)
  • Finkelstein et al., J. Dent. Res., vol. 58, No. 3, 1034-1039, (1979)
  • Wright et al., Clinical Preventive Dentistry, vol. 1, No. 3, (1979)
  • Wright et al., J. Dent. Res., vol. 56, No. 6, (1977)
  • Van Swol et al., Military Medicine, 391-394 (1977)
  • Horowitz et al., J. Den. Res., 56: 1977 Spec. Iss.
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