Retinal, derivatives and their therapeutic use
Patent 5093360 Issued on March 3, 1992. Estimated Expiration Date: 
April 7, 2009. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
April 7, 2009. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesProcess for the treatment of acne vulgaris utilizing retinal Treatment of skin keratoses with retinal Methods for treatment of sundamaged human skin with retinoids Patent #: 4888342 InventorsApplicationNo. 334518 filed on 04/07/1989US Classes:514/463, Plural ring oxygens in the hetero ring514/468, Polycyclo ring system having the hetero ring as one of the cyclos514/470, Chalcogen or nitrogen bonded directly to the hetero ring514/529, Z-C(=O)-O-Y wherein Z is hydrogen or an organic radical bonded to the C(=O) by a carbon and Y is an organic radical bonded to the oxygen by a carbon514/693, Aldehyde DOAI514/698, With preservative or stabilizer514/701, Acyclic carbon to carbon unsaturation514/703, Carbon to carbon unsaturation514/715, Ether DOAI514/725, Vitamin A compound or derivative514/859, Acne514/863PsoriasisExaminersPrimary: Shah, Mukund J.Assistant: Ward, E. C. Attorney, Agent or FirmInternational ClassesA61K 031/075A61K 031/11 A61K 031/33 AbstractTherapeutic as well as preventive measures to improve cosmetic conditions and to alleviate the symptoms of dermatologic disorders with retinal and its derivatives is disclosed. Cosmetic conditions and dermatologic disorders in humans and domestic animals in which retinal and its derivatives may be useful include age spots, wrinkles, warts, eczema, seborrheic keratoses, acne, oily skin, psoriasis, dandruff, xerosis, inflammatory and pruritic skin, disturbed keratinization skin changes associated with aging and possibly viral infections. Retinal and its derivatives include their stereoisomers, for example, all-trans, 13-cis, 11-cis, 9-cis, 7-cis, 11,13-cis and 9,13-cis vitamin A aldehydes, their hydrate, hemiacetal and acetal forms, and their adduct compounds. Compositions containing retinal or its derivative may be administered systemically such as orally, or topically to the affected areas of the skin.Field of SearchAldehyde DOAIWith preservative or stabilizer Acyclic carbon to carbon unsaturation Carbon to carbon unsaturation Polycyclo ring system having the hetero ring as one of the cyclos Z-C(=O)-O-Y wherein Z is hydrogen or an organic radical bonded to the C(=O) by a carbon and Y is an organic radical bonded to the oxygen by a carbon Vitamin A compound or derivative Ether DOAI Chalcogen or nitrogen bonded directly to the hetero ring Acne Psoriasis Plural ring oxygens in the hetero ring | |
