U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Multilayer sustained release granule

Patent 5093200 Issued on March 3, 1992. Estimated Expiration Date: Icon_subject March 3, 2009. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3577512

Nitrofurantoin sustained release tablet
Patent #: 4122157
Issued on: 10/24/1978
Inventor: Huber

Prolonged-release pharmaceutical compositions for oral administration, their methods of making and use
Patent #: 4155993
Issued on: 05/22/1979
Inventor: Belleville ,   et al.

Theophylline sustained release granule
Patent #: 4261970
Issued on: 04/14/1981
Inventor: Ogawa ,   et al.

Sustained release pharmaceutical compositions
Patent #: 4309405
Issued on: 01/05/1982
Inventor: Guley ,   et al.

Sustained release pharmaceutical compositions
Patent #: 4309406
Issued on: 01/05/1982
Inventor: Guley ,   et al.

Protective coating compositions
Patent #: 4341563
Issued on: 07/27/1982
Inventor: Kurihara ,   et al.

Sustained release pharmaceutical composition of solid medical material
Patent #: 4404183
Issued on: 09/13/1983
Inventor: Kawata ,   et al.

Prolonged-action multiple-layer tablets
Patent #: 4454108
Issued on: 06/12/1984
Inventor: Iida ,   et al.

Long-lasting three-layered pharmaceutical film preparations
Patent #: 4483846
Issued on: 11/20/1984
Inventor: Koide ,   et al.

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Inventors

Application

No. 253367 filed on 09/30/1988

US Classes:

428/407, Including synthetic resin or polymer424/468, Sustained or differential release type424/472, Layered unitary dosage forms424/476, Containing waxes, higher fatty acids, higher fatty alcohols, or derivatives thereof (e.g., chocolate)424/494, Cellulose derivatives424/498, Containing waxes, higher fatty acids, higher fatty alcohols, or derivatives thereof428/402.2, Microcapsule with fluid core (includes liposome)428/402.21, Solid-walled microcapsule from synthetic polymer428/402.24, Microcapsule with solid core (includes liposome)428/403Coated

Examiners

Primary: Lesmes, George F.
Assistant: Brown, Christopher

Attorney, Agent or Firm

Foreign Patent References

  • 2721603 DE 05/13/1976

International Classes

B32B 027/00
A61K 009/56

Foreign Application Priority Data

1985-10-23 JP

Abstract

A multilayer granule of the invention comprises a core, a slow-release layer, a rapid-release layer to be provided outer of said slow-release layer and a film layer containing a metal stearate and being deposited between the slow-release layer and the rapid-release layer. A pharmacologically effective component is kept to discharge for long.

Other References

  • "Stearate" Definition: Hackh's Chemical Dictionary-4th ed., Ed.; Julius Gran
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