U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Process for producing magnetically responsive polymer particles and application thereof

Patent 5091206 Issued on February 25, 1992. Estimated Expiration Date: Icon_subject May 30, 2009. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Magnetic particles for immunoassay
Patent #: 4177253
Issued on: 12/04/1979
Inventor: Davies ,   et al.

Polymer filler particles with filler free coating
Patent #: 4490436
Issued on: 12/25/1984
Inventor: Kawakami ,   et al.

Binding assays employing magnetic particles Patent #: 4628037
Issued on: 12/09/1986
Inventor: Chagnon ,   et al.

Inventors

Assignee

Application

No. 337511 filed on 05/30/1989

US Classes:

427/2.18, En masse rotating means employed (e.g., rotating pan, tumbling)427/128, Magnetic coating427/131, Applying superposed diverse coating or coating a coated base427/214, Applying superposed diverse coatings or coating a coated base427/222, Resin base436/513, INVOLVING IGA, IGD, IGE, OR IGM436/526Magnetic

Examiners

Primary: Kepplinger, Esther M.
Assistant: Stall, Jacintha M.

Attorney, Agent or Firm

Foreign Patent References

  • 83/03920 WO. 11/25/1983

International Classes

A01N 001/02
B05D 005/12
B05D 007/00

Abstract

This invention provides a novel process of producing magnetically responsive polymer particles comprising polymeric core particles coated evenly with a layer of polymer containing magnetically responsive metal oxide. A wide variety of polymeric particles with sizes ranging from 1 to 100 microns can be used a core particles and transformed into magnetically responsive polymer particles. The surface of these magnetically responsive polymer particles can be coated further with another layer of functionalized polymer. These magnetically responsive polymer particles can be used for passive or covalent coupling of biological material such as antigens, antibodies, enzymes of DNA/RNA hybridization and used as solid phase for various types of immunoassays, DNA/RNA hybridization probes assays, affinity purification, cell separation and other medical, diagnostic, and industrial applications.

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