Patent ReferencesMagnetic particles for immunoassay Polymer filler particles with filler free coating Binding assays employing magnetic particles Patent #: 4628037 InventorsAssigneeApplicationNo. 337511 filed on 05/30/1989US Classes:427/2.18, En masse rotating means employed (e.g., rotating pan, tumbling)427/128, Magnetic coating427/131, Applying superposed diverse coating or coating a coated base427/214, Applying superposed diverse coatings or coating a coated base427/222, Resin base436/513, INVOLVING IGA, IGD, IGE, OR IGM436/526MagneticExaminersPrimary: Kepplinger, Esther M.Assistant: Stall, Jacintha M. Attorney, Agent or FirmForeign Patent References
International ClassesA01N 001/02B05D 005/12 B05D 007/00 AbstractThis invention provides a novel process of producing magnetically responsive polymer particles comprising polymeric core particles coated evenly with a layer of polymer containing magnetically responsive metal oxide. A wide variety of polymeric particles with sizes ranging from 1 to 100 microns can be used a core particles and transformed into magnetically responsive polymer particles. The surface of these magnetically responsive polymer particles can be coated further with another layer of functionalized polymer. These magnetically responsive polymer particles can be used for passive or covalent coupling of biological material such as antigens, antibodies, enzymes of DNA/RNA hybridization and used as solid phase for various types of immunoassays, DNA/RNA hybridization probes assays, affinity purification, cell separation and other medical, diagnostic, and industrial applications.Field of SearchMAGNETIC BASE OR COATINGMagnetic coating With pretreatment of base With post-treatment of coating or coating material Applying superposed diverse coating or coating a coated base PARTICLES, FLAKES, OR GRANULES COATED OR ENCAPSULATED Applying superposed diverse coatings or coating a coated base Metal base Metal coating Resin, rubber, or hardenable oil containing coating Resin base Proteinaceous coating Metal coating Metal base Synthetic resin coating Metal base Protein or derivative containing coating (e.g., casein, glue, gelatin, etc.) Oxide-containing coating With wax, bitumen, resin, or gum Synthetic resin Free metal or alloy containing Iron-oxygen compound containing |
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