Novel microproteins
Patent 5089474 Issued on February 18, 1992. Estimated Expiration Date: 
May 24, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
May 24, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesElastase inhibitors, a process for their preparation and medicaments containing these inhibitors Serine protease inhibitors Patent #: 4829052 InventorsAssigneeApplicationNo. 528834 filed on 05/24/1990US Classes:514/12, 25 or more peptide repeating units in known peptide chain structure530/32425 or more amino acid residues in defined sequenceExaminersPrimary: Russel, Jeffrey E.Assistant: Walsh, Stephen Attorney, Agent or FirmForeign Patent References
International ClassesA61K 037/02A61K 037/64 C07K 001/04 C07K 007/10 Foreign Application Priority Data1989-05-31 FRAbstractA microprotein containing 28 amino acids of the formula ##STR1## wherein the X in position 4 is a residue of a member of the group consisting of valine, leucine, isoleucine, norleucine, alanine, cyclohexylalanine, o-methylthreonine, phenylglycine or -amino butyric acid, Arginine, Y in position 5 is a residue of isoleucine or serine, Z in position 7 is a residue of methionine or norleucine, with the proviso that Z is a norleucine residue when X is an Arginine residue, having anti-elastase activity. |
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