Detection of human tumor progression and drug resistance
Patent 5085983 Issued on February 4, 1992. Estimated Expiration Date: 
May 17, 2009. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
May 17, 2009. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesProcess for amplifying, detecting, and/or-cloning nucleic acid sequences Methods and compositions for detecting human tumors Patent #: 4699877 InventorAssigneeApplicationNo. 352994 filed on 05/17/1989US Classes:435/6, Involving nucleic acid435/91.2, Acellular exponential or geometric amplification (e.g., PCR, etc.)436/94, Saccharide (e.g., DNA, etc.)436/501, BIOSPECIFIC LIGAND BINDING ASSAY536/24.3, Probes for detection of specific nucleotide sequences or primers for the synthesis of DNA or RNA536/24.31, Probes for detection of animal nucleotide sequences536/24.32Probes for detection of microbial nucleotide sequencesExaminersPrimary: Wax, Robert A.Assistant: Zitomer, Stephanie W. Attorney, Agent or FirmInternational ClassesC12Q 001/68C12P 019/34 G01N 033/566 C07H 015/12 AbstractChanges in tumor cell RNA and DNA are utilized to detect the progression and the temporal changes in resistance to chemotherapy in human tumors.Other References
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