U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Pharmaceutical granulate

Patent 5085869 Issued on February 4, 1992. Estimated Expiration Date: Icon_subject February 24, 2009. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Slow-releasing medical preparation to be administered by adhering to a wet mucous surface
Patent #: 4292299
Issued on: 09/29/1981
Inventor: Suzuki ,   et al.

Prolonged-action multiple-layer tablets
Patent #: 4454108
Issued on: 06/12/1984
Inventor: Iida ,   et al.

Solid nifedipine preparations and a process for preparing same
Patent #: 4665081
Issued on: 05/12/1987
Inventor: Doi ,   et al.

Sustained release tablets
Patent #: 4753801
Issued on: 06/28/1988
Inventor: Oren ,   et al.

Oral sustained release pharmaceutical preparation
Patent #: 4777033
Issued on: 10/11/1988
Inventor: Ikura ,   et al.

Novel controlled release formulations of tetracycline compounds Patent #: 4837030
Issued on: 06/06/1989
Inventor: Valorose, Jr. ,   et al.

Inventors

Assignee

Application

No. 315268 filed on 02/24/1989

US Classes:

424/499, Contains proteins or derivative or polysaccharides or derivative424/494, Cellulose derivatives424/686, Carbonate or bicarbonate424/692, Magnesium hydroxide or oxide514/819ANTACID, ORAL

Examiners

Primary: Page, Thurman K.
Assistant: Hulina, Amy

Attorney, Agent or Firm

Foreign Patent References

  • 0049061 EP. 04/13/1982
  • 0080862 EP. 08/13/1983
  • 0159735 EP. 10/13/1985
  • 0281200 EP. 09/13/1988
  • 2058565 GB. 04/13/1981
  • 2172006 GB. 09/13/1986

International Classes

A61K 009/16
A61K 033/06

Foreign Application Priority Data

1988-02-25 EP

Abstract

A wet granulate is provided for therapeutically useful substances having a water solubility 10 wt % or less and microcrystalline or microfine cellulose or a mixture of both, where substantial amounts of wet binders are avoided.Tableting mixtures with the new granulate possess a good flow pattern and may be compressed to tablets which show an excellent disintegration behavior.

Other References

  • The Merck Index, 10th Ed., (1983), p. 810, reference no. 5478, "Magnesium Carbonate Hydroxide
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