Sustained release pharmaceutical preparations containing an analgesic and a decongestant
April 12, 2009. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3567819 Pharmaceutical compositions Method and preparation for administration to the mucosa of the oral or nasal cavity Method and preparation for administration to the mucosa of the oral or nasal cavity Edible unit dosage form consisting of outer mannitol shell and inner liquid or gel center and method for manufacturing the same Thixotropic compositions easily convertible to pourable liquids Simultaneous delivery of two drugs from unit delivery device Controlled release dosage form comprising acetaminophen, pseudoephedrine sulfate and dexbrompheniramine maleate Controlled release dosage form comprising acetaminophen, pseudoephedrine sulfate and dexbrompheniramine maleate Sustained release dosage form based on highly plasticized cellulose ether gels InventorApplicationNo. 336929 filed on 04/12/1989US Classes:424/472, Layered unitary dosage forms424/465, With claimed perfecting feature in contents (e.g., excipient, lubricant, etc.)424/468, Sustained or differential release type424/469, Discrete particles in supporting matrix424/470, Where particles are granulated424/480, Cellulose or derivative514/853DECONGESTANTExaminersPrimary: Page, Thurman K.Assistant: Spear, James M. Attorney, Agent or FirmForeign Patent References
International ClassesA61K 009/22A61K 009/24 AbstractAn orally administrable sustained-release pharmaceutical tablet having at least two layers, which are directly compressible, is disclosed. The first layer, an immediate-release layer, contains an orally active analgesic and is readily susceptible to disintegration in the stomach. The second layer, a sustained-release layer which is directly compressed onto the first layer, comprises an orally active decongestant admixed with a major amount of a sustained-release agent so as to display increased resistance to disintegration and erosion in the gastro-intestinal tract relative to the first layer.Other References
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