U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Pentamidine salts useful in the treatment of pneumocystis carinii pneumonia

Patent 5084480 Issued on January 28, 1992. Estimated Expiration Date: Icon_subject July 19, 2009. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

2204983

2277861

2277862

2410796

2424325

2425223

2449724

3105853

Bis-(meta-amidinophenoxy)-compounds and pharmacologically acceptable acid addition salts thereof
Patent #: 4034010
Issued on: 07/05/1977
Inventor: Hamano ,   et al.

Aromatic amidines as antiviral agents in animals
Patent #: 4097525
Issued on: 06/27/1978
Inventor: Kraska ,   et al.

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Inventors

Assignee

Application

No. 383243 filed on 07/19/1989

US Classes:

514/554, Amine addition salt of the acid562/587, Polyoxy562/589Lactic acid per se or salt thereof

Examiners

Primary: Gray, Bruce

Attorney, Agent or Firm

Foreign Patent References

  • 729847 GB. 02/11/2012

International Class

A61K 031/205

Abstract

Salts of pentamidine, formulations containing such salts and the use of such salts of treatment or prophylaxis of pneumocystis carinii. Pentamidine gluconate and lactate has been discovered and found to have high water solubility while providing potentially less toxic alternatives to pentamidine isethionate, especially for aerosolized administration to patients suffering from acquired immunodeficiency syndrome, AIDS, or AIDS related complex, ARC.

Other References

  • Hawley, Gessner G., The Condensed Chemical Dictionary, Von Nostrand Reinhold Co., New York, 10th Ed., p. 143, (1983)
  • A Chemotherapeutic Comparison of the Trypanocidal Action of Some Aromatic Diamidine Ashley et al., 1942
  • PENTAM™ 300 Package Insert, (no date), p. 120
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