...that several people are credited with the invention of the flush toilet? Most people have heard of Thomas Crapper (1837-1910), the sanitary engineer who invented the valve-and-siphon arrangement that made the modern toilet possible. Another claimant to "the throne" was British inventor Alexander Cumming who patented a toilet in 1775. Then there's a nameless Minoan (a native of ancient Crete) who lived 4,000 years ago who supposedly was ahead of his time and created the first flush toilet!
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AbstractSalts of pentamidine, formulations containing such salts and the use of such salts of treatment or prophylaxis of pneumocystis carinii. Pentamidine gluconate and lactate has been discovered and found to have high water solubility while providing potentially less toxic alternatives to pentamidine isethionate, especially for aerosolized administration to patients suffering from acquired immunodeficiency syndrome, AIDS, or AIDS related complex, ARC.Other References
| InventorsAssigneeApplicationNo. 383243 filed on 07/19/1989US Classes:514/554, Amine addition salt of the acid562/587, Polyoxy562/589Lactic acid per se or salt thereofField of Search562/589, Lactic acid per se or salt thereof562/587, Polyoxy514/554Amine addition salt of the acidExaminersPrimary: Gray, BruceAttorney, Agent or FirmUS Patent References2204983, 2277861, 2277862, 2410796, 2424325, 2425223, 2449724, 3105853, 4034010, Bis-(meta-amidinophenoxy)-compounds and pharmacologically acceptable acid addition salts thereofIssued on: 07/05/1977 Inventor: Hamano , et al.4097525, Aromatic amidines as antiviral agents in animals Issued on: 06/27/1978 Inventor: Kraska , et al.4367231, Method of using octahydro pyrazolo[3,4-g]quinolines Issued on: 01/04/1983 Inventor: Kornfeld , et al.4501890Trans-( b1;)-2,4,6-substituted-5,5a,6,7,8,9,9a,10-octahydro-pyrimido[4,5-g]quino lines Issued on: 02/26/1985 Inventor: Nichols , et al. Foreign Patent References
International ClassA61K 031/205 |