Method of preparing oral dosage forms with a granulating composition
Patent 5073377 Issued on December 17, 1991. Estimated Expiration Date: 
October 4, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
October 4, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesGranular calcium hypochlorite coated with an inorganic salt Directly compressible acetaminophen granulation Chewable mineral supplement Patent #: 4582709 InventorsAssigneeApplicationNo. 592613 filed on 10/04/1990US Classes:424/458, Containing discrete coated particles pellets, granules, or beads424/439, Food or edible as carrier for pharmaceutical424/441, Chewable tablet or wafer424/461, Containing polysaccharide (e.g., cellulose sugars, etc.)424/462, Containing solid synthetic polymers424/465, With claimed perfecting feature in contents (e.g., excipient, lubricant, etc.)424/466, Effervescent424/493, Containing polysaccharides (e.g., sugars)424/494, Cellulose derivatives424/495, Ethyl cellulose424/497, Containing solid synthetic polymers424/498Containing waxes, higher fatty acids, higher fatty alcohols, or derivatives thereofExaminersPrimary: Page, Thurman K.Assistant: Spear, James M. Attorney, Agent or FirmInternational ClassesA61K 009/26A61K 009/46 AbstractThe invention involves a granulating composition composed of an aqueous solution of magnesium sulfate heptahydrate and sodium hexametaphosphate. This composition can be used to prepare granules of ingredients for inclusion in any formulation for which rapid disintegration or dispersion are important factors. It is useful for tablets containing ingredients which are difficult to compress and is particularly useful for formulating swallowable tablets of a single non-soluble ingredient such as calcium carbonate. Disintegration times are markedly decreased. | |
