U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Purified activin B composition

Patent 5071834 Issued on December 10, 1991. Estimated Expiration Date: Icon_subject October 12, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Novel human physiologically active polypeptide Patent #: 4879226
Issued on: 11/07/1989
Inventor: Wallace, et al.

Inventors

Application

No. 597293 filed on 10/12/1990

US Classes:

514/12, 25 or more peptide repeating units in known peptide chain structure514/8, Glycoprotein (carbohydrate containing)514/21, Produced by or extracted from animal tissue530/399Hormones, e.g., prolactin, thymosin, growth factors, etc.

Examiners

Primary: Schain, Howard E.
Assistant: Koh, Choon P.

Attorney, Agent or Firm

Foreign Patent References

  • 0210461 EP. 02/13/1987
  • 0222491 EP. 05/13/1987
  • WO86/06076 WO. 10/13/1986

International Classes

A61K 037/02
A61K 037/43

Abstract

A pharmaceutical composition and method are provided for erythropoietin therapy, such as treatment of an anemic disease, wherein an effective amount of activin with two betaB chains formulated in a pharmaceutically acceptable carrier is administered to a patient or animal in need of such therapy. Preferably the activin is human and the composition is administered parenterally.

Other References

  • Mason, T., "Nonsteroidal Gonadal Factors: Physiological Roles and Possibilities in Contraceptive Development", Hodgen et al., Eds., Jones Institute Press, Norfolk, Va., pp. 19-29 (1988)
  • Mason et al., Biochem. Biophys. Res. Commun. 135 (3):957-964 (1986)
  • Mason et al., "Inhibin-Non-Steroidal Regulation of Follicle Stimulating Hormone Secretion", Serono Symposia Publications from Raven Press, vol. 42, pp. 77-88 (1987)
  • Eto et al., Biochem. Biophys. Res. Commun, 142 (3):1095-1103 (1987)
  • Murata et al., Proc. Natl. Acad. Sci. U.S.A. 85:2434-2438 (1988)
  • Yu et al., Nature 330:765-767 (1987)
  • Ikawa et al., Gann 66:583-584 (1975)
  • Murata et al., Biochem. Biophys. Res. Commun. 151 (1):230-235 (1988)
  • Mason et al., Molecular Endocrinology, 3:1352-1358 (1989
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