U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Transdermal administration of buprenorphine

Patent 5069909 Issued on December 3, 1991. Estimated Expiration Date: Icon_subject June 20, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3433791

Trandermal delivery of opioids
Patent #: 4626539
Issued on: 12/02/1986
Inventor: Aungst ,   et al.

Transdermal absorption dosage unit for narcotic analgesics and antagonists and process for administration
Patent #: 4806341
Issued on: 02/21/1989
Inventor: Chien ,   et al.

Transdermal drug delivery using a dual permeation enhancer and method of performing the same Patent #: 4956171
Issued on: 09/11/1990
Inventor: Chang

Inventors

Assignee

Application

No. 540908 filed on 06/20/1990

US Classes:

424/449, Transdermal or percutaneous424/448, Pressure sensitive adhesive means514/947Topical application

Examiners

Primary: Page, Thurman K.
Assistant: Phelan, D. Gabrielle

Attorney, Agent or Firm

Foreign Patent References

  • 282156 EP. 09/13/1988
  • WO8801497 WO. 03/13/1988
  • WO8809676 WO. 12/13/1988

International Class

A61F 013/00

Abstract

Method and laminated composite for administering buprenorphine transdermally to treat pain. The composite comprises an impermeable backing layer and a reservoir layer containing buprenorphine and optionally a permeation enhancer combined with a pressure-sensitive adhesive with the amounts of buprenorphine and optional enhancer being sufficient to cause the buprenorphine to pass through the skin at a rate in excess of about 0.05 mcg/cm2 /hr.

Other References

  • Adriensen, H. et al., Acta. Anaesthesia Belg. (1985) 36:33-40
  • Bickel, W. K. et al., Chem. Pharmacol. Ther. (1990) 43:72-78
  • Bullingham, R. et al., Clin. Pharmacol. Ther. (1980) 28:667-72
  • Bullingham, R. et al., Clin. Pharmacol. (1983) 8:332-43
  • Bullingham, R. et al., British Clin. Pharmacol. (1982) 13:665-73
  • Fudala, P. J. et al., Clin. Pharmacol Ther. (1990) 47:4:525-534
  • Heel, R. C. et al., "Buprenorphine: A Review of Its Pharmacological Properties and Therapeutic Efficacy", Drugs (1979) 17:81-110
  • O'Sullivan, G. H. et al., Anaesthesia (1983) 38:977-84
  • Ostrowski, M. J. et al., British J. Clin. Pharmacol. (1979) 33:587-90
  • Rosana, C. et al., Clin. Ther. (1982) 5:61-8
  • Martindale: The Extra Pharmacopeia, Entry 6209-w (Buprenorphine Hydrochloride), London: The Pharmaceutical Press, 1989
  • Physician's Desk Reference, 43rd Edition, pp. 1476-1477 ("Buprenex") (1989
PatentsPlus Images
Enhanced PDF formats
loading...
PatentsPlus: add to cart
PatentsPlus: add to cartSearch-enhanced full patent PDF image
$9.95more info
PatentsPlus: add to cart
PatentsPlus: add to cartIntelligent turbocharged patent PDFs with marked up images
$16.95more info
 
Sign InRegister
Username  
Password   
forgot password?