U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

3-arylcarbonyl-1-(C-attached-N-heteryl)-1H-indoles

Patent 5068234 Issued on November 26, 1991. Estimated Expiration Date: Icon_subject February 26, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Re32761

3489770

Indole derivatives
Patent #: 3946029
Issued on: 03/23/1976
Inventor: Descamps ,   et al.

Indole derivatives and process for preparing the same
Patent #: 4139634
Issued on: 02/13/1979
Inventor: Pigerol ,   et al.

3-arylcarbonyl- and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles, compositions and use
Patent #: 4581354
Issued on: 04/08/1986
Inventor: Bell

3-arylcarbonyl-and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles Patent #: 4634776
Issued on: 01/06/1987
Inventor: Bell

Inventors

Assignee

Application

No. 484759 filed on 02/26/1990

US Classes:

514/235.2, Ring nitrogen in the bicyclo ring system514/228.2, Polycyclo ring system having the additional hetero ring as one of the cyclos544/61, The additional hetero ring is one of the cyclos in a bicyclo ring system544/143The five-membered hetero ring is one of the cyclos in a bicyclo ring system

Examiners

Primary: Ivy, C. Warren
Assistant: Chang, Ceila

Attorney, Agent or Firm

International Classes

C07D 417/06
C07D 413/06
A61K 031/54
A61K 031/535

Abstract

2-R2 -R4 -substituted-3-R3 -CO-1-[(C-attached-N-herteryl)-(Alk)n ]-1H-indoles useful as analgesic, anti-rheumatic, anti-inflammatory or anti-glaucoma agents.

Other References

  • Inion et al., Europ. J. of Med. Chem., 10(3), 276-285 (1975)
  • Tambute, Acad. Sci. Comp. Rend., Ser. C 278(20), 1239-1242 (1974)
  • Dalla Croce, Chem. Abst., 80, 95655f (1974)
  • Bosch et al., Tetrahedron, 40(8), 1419-24 (1984)
  • Bosch et al., J. Org. Chem., 48(25), 4836-41 (1983)
  • Bennasar et al., Tetrahedron, 42(2), 637-647 (1986)
  • Vartangan et al., Ann. Khim. Zh., 38(5), 308-313 (1985)
  • Chem. Abst. 105, 114874e (1985)
  • Nilsson et al., Acta. Chem. Scand., Ser. B, B39(7), 531-537 (1985)
  • Sasakura et al., Syn. Comm. 18(3), 265-273 (1988
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