Patent ReferencesPhenylbutanol derivatives Patent #: 3936468 InventorsAssigneeApplicationNo. 605817 filed on 10/30/1990US Classes:514/279Polycyclo ring system having the six-membered hetero ring as one of the cyclosExaminersPrimary: Friedman, Stanley J.Attorney, Agent or FirmInternational ClassA61K 031/44AbstractThis invention provides trans-3,4 1-substituted-3-substituted-4-methyl-4-(3-substituted phenyl)piperidines as opioid antagonists capable of blocking the mu or kappa receptors in the brain. | |