Patent ReferencesMethod for treatment of acne Clear cosmetic sticks Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl) pyrrolidone Penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one Patent #: 4557934 Inventors
ApplicationNo. 500236 filed on 03/26/1990US Classes:514/31, The hetero ring has 20 or more ring carbons (e.g., nystatin, etc.)536/6.5Oxygen containing hetero ring having at least twenty members (e.g., amphotericin, nystatin, pimaricin, etc.)ExaminersPrimary: Peselev, ElliAttorney, Agent or FirmForeign Patent References
International ClassesA61K 031/70C07H 017/08 Foreign Application Priority Data1985-11-27 HUAbstractThis invention relates to a primycin-containing colloidal basic gel comprising 5-30% of primycin and 95-70% of N-methyl-pyrrolidone-2. The invention also relates to antibacterial compositions particularly for the treatment of acne vulgaris comprising as active ingredient 0.1-100% of a primycin-containing colloidal basic gel, if desired together with further antimicrobial active ingredients, in admixture with 99.9-0% of usual inert pharmaceutical filling, diluting and other formulating additives. The invention also relates to combination composition comprising as active ingredient 1-60% of a primycin-containing colloidal basic gel and 0.1-40% of further pharmaceutical active ingredient(s), e.g. one or more antibiotic(s), chemotherapeutical agent(s), fungistatic or fungicidal agent(s), steroidal or non-steroidal antiinflammatory agent (s), epithelogenic agent(s), local anaesthetic(s), and/or vitamin(s).Other References
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