Method of manufacturing a plurality of uniform microfabricated sensing devices having an immobilized ligand receptor
August 15, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3572400 3776819 Detection of catalase-containing bacteria Membrane for enzyme electrodes Selective chemical sensitive FET transducer Element, structure and method for the analysis or transport of liquids Method for making substance-sensitive electrical structures by processing substance-sensitive photoresist material Process for the recovery of immunoglobulins Permselective membrane compositions for gas separations and process for the separation of gases therewith Diagnostic device incorporating a biochemical ligand Inventors
AssigneeApplicationNo. 567870 filed on 08/15/1990US Classes:435/4, MEASURING OR TESTING PROCESS INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITION OR TEST STRIP THEREFORE; PROCESSES OF FORMING SUCH COMPOSITION OR TEST STRIP204/403.1, Enzyme included in apparatus204/403.11, Glucose oxidase204/415, Selectively permeable membrane204/418, Organic membrane257/253, Chemical (e.g., ISFET, CHEMFET)422/57, Having coated reagent422/930, Drop counters or drop formers [B01L 3/02D]427/2.13, Layer formed contains chemical reagent or chemically reacts with substrate (e.g., cell stain or fix, pH paper, immobilized antigen)427/407.1, Synthetic resin coating427/414, Protein or derivative containing coating (e.g., casein, glue, gelatin, etc.)435/7.1, Involving antigen-antibody binding, specific binding protein assay or specific ligand-receptor binding assay600/345ElectroanalysisExaminersPrimary: Beck, ShriveAssistant: Owens, Terry J. Attorney, Agent or FirmForeign Patent References
International ClassG01N 033/53AbstractA plurality of uniform microfabricated sensing devices are produced by establishing a plurality of base sensors on a substrate wafer, forming over at least a portion of each base sensor a permselective layer, superimposing a photoformable proteinaceous photoresist layer over a substantial portion of the permselective layer, and forming a topmost layer of an immobilized ligand receptor. The ligand receptor and corresponding ligand may be immunoreactive species.Other References
Field of SearchSynthetic resin coatingProtein or derivative containing coating (e.g., casein, glue, gelatin, etc.) Selectively permeable membrane Ion-sensitive electrode Organic membrane Having coated reagent In holder or container having special form Involving antigen-antibody binding, specific binding protein assay or specific ligand-receptor binding assay ENZYME OR MICROBE ELECTRODE INVOLVING AN INSOLUBLE CARRIER FOR IMMOBILIZING IMMUNOCHEMICALS OPTICAL PROPERTY Tube, bottle, or dipstick |
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