U.S. patents available from 1976 to present.
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Human hematopoietic stem cell

Patent 5061620 Issued on October 29, 1991. Estimated Expiration Date: Icon_subject March 30, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Human stem cells Patent #: 4714680
Issued on: 12/22/1987
Inventor: Civin

Inventors

Assignee

Application

No. 502616 filed on 03/30/1990

US Classes:

435/7.21, Animal cell435/372Blood, lymphatic, or bone marrow origin or derivative

Examiners

Primary: Weimar, Elizabeth C.
Assistant: Wang, Gian P.

Attorney, Agent or Firm

International Classes

C12N 005/00
C12Q 001/00
G01N 033/53

Abstract

Human hematopoietic stem cells are provided by separation of the stem cells from dedicated cells. The stem cells may than be maintained by regeneration in an appropriate growth medium. Means are provided for assaying for the stem cells as to their capability for producing members of each of the hematopoietic lineages.

Other References

  • Muller-Sieberg et al. (1988), J. Exp. Med., vol. 167: 1825-1840
  • Kurtzberg et al. (1989), PNAS: vol. 86: 7575-7579
  • Folks et al. (1988), Science: vol. 242: 919-922
  • Lu et al. (1987), Journal of Immunology: vol. 139: 1823-1829
  • Lewinsohn et al., Blood: vol. 75: 589-595 (1990)
  • Gishen et al. (1987), J. of Immunology 138: 2433-243
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