U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Skin permeation enhancer compositions, and methods and transdermal systems associated therewith

Patent 5053227 Issued on October 1, 1991. Estimated Expiration Date: Icon_subject June 12, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3472931

3551554

3598122

3598123

3731683

3742951

3797494

3854480

3923989

3926188

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Inventors

Assignee

Application

No. 537080 filed on 06/12/1990

US Classes:

424/448, Pressure sensitive adhesive means424/447, Bandages with incorporated medicaments424/449, Transdermal or percutaneous514/946, PENETRANT OR ABSORBENT (ENHANCES PENETRATION INTO SUBJECT TREATED)514/947Topical application

Examiners

Primary: Page, Thurman K.
Assistant: Horne, Leon R.

Attorney, Agent or Firm

Foreign Patent References

  • 0235090 EP. 09/13/1987
  • 0261429 EP. 03/13/1988
  • 0275716 EP. 07/13/1988
  • 0279982 EP. 08/13/1988
  • 0285563 EP. 10/13/1988
  • 88/01496 WO. 03/13/1988

International Class

A61F 013/02

Abstract

Skin permeation enhancer compositions are provided which increase the permeability of skin to transdermally administered pharmacologically active agents. The composition contains diethylene glycol monoethyl or monomethyl ether in addition to an ester component such as propylene glycol monolaurate, methyl laurate or the like. The compositions are particularly useful in conjunction with the transdermal administration of steroid drugs such as progestogens and estrogens. Methods and drug delivery systems for using the enhancer compositions are provided as well.

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