Patent ReferencesMethod of determining pressure within liquid containing vessel Ultrasonic image enhancement Microbubble precursors and methods for their production and use Contact agents for ultrasonic imaging Ultrasonic diagnosing apparatus Ultrasonic diagnostic apparatus Contactless comminution of concrements in the body of a living being Apparatus and method for triggering shock waves in lithotripsy Patent #: 4685461 InventorAssigneeApplicationNo. 273570 filed on 11/21/1988US Classes:600/431, Detectable material placed in body600/454, Blood flow studies600/458, Contrast enhancement601/2, Ultrasonic604/890.1CONTROLLED RELEASE THERAPEUTIC DEVICE OR SYSTEMExaminersPrimary: Cohen, Lee S.Assistant: Zele, John D. Attorney, Agent or FirmForeign Patent References
International ClassA61B 001/00Foreign Application Priority Data1987-11-24 JPAbstractAn ultrasonic measuring apparatus and method operating as an ultrasonic echocardiograph and a doppler blood flow speed meter by creating numerous microbubbles as a contrast medium or reflector only in an intended blood vessel. The apparatus comprises an injector which injects into a vein of patient an agent which is a substance encapsulated in numerous microcapsules of several micrometer or less in diameter and distributed in a carrier liquid so that it produces microbubbles through the reaction with blood, and a shock wave transmitter which emits a shock wave with the dominant positive pressure from the body surface toward a specific blood vessel such as the root of the aorta so that only microcapsules in the specific blood vessel, among all dispersed in the whole body, are broken by the shock wave and the agent is released in the blood flow.Other References
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