U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Indole derivative

Patent 5037845 Issued on August 6, 1991. Estimated Expiration Date: Icon_subject March 1, 2009. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3322787

3624103

3-Amino or amido-2-(1H-indol-3-yl) propanoic acid derivatives
Patent #: 4283410
Issued on: 08/11/1981
Inventor: Schut ,   et al.

Heterocyclic compounds Patent #: 4816470
Issued on: 03/28/1989
Inventor: Dowle ,   et al.

Inventor

Assignee

Application

No. 317682 filed on 03/01/1989

US Classes:

514/415, The bicyclo ring system consists of the five-membered hetero ring and a benzene ring (e.g., indole, etc.)548/504Nitrogen attached indirectly to ring carbon of the five-membered hetero ring by acyclic nonionic bonding (e.g., tryptamine, etc.)

Examiners

Primary: Ceperley, Mary E.

Attorney, Agent or Firm

Foreign Patent References

  • 145459 EP. 06/13/1985
  • 8115513 FR. 02/13/1982
  • 8115514 FR. 02/13/1982
  • 8115515 FR. 02/13/1982
  • 8309429 FR. 01/13/1984
  • 8418618 FR. 06/13/1985

International Classes

A61K 031/40
C07D 209/16

Foreign Application Priority Data

1984-08-01 GB

Abstract

A compound of formula (I) ##STR1## and its physiologically acceptable salts and solvates are described as useful in treating and/or preventing pain resulting from dilatation of the cranial vasculature in particular migraine.The compound (I) may be prepared, for example, by cyclizing a compound of formula (II) ##STR2##

Other References

  • M. Dorole et al., Chem. Abst., vol. 100, No. 103175y (1983
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