Method of stabilizing tretinoin
Patent 5037655 Issued on August 6, 1991. Estimated Expiration Date: 
April 18, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
April 18, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3906108 High potency vitamin A compositions Treatment of skin keratoses with retinal Tretinoin in a gel vehicle for acne treatment Vitamin A compositions Aqueous solution containing lipid-soluble pharmaceutical substance Patent #: 4840970 InventorApplicationNo. 510832 filed on 04/18/1990US Classes:424/427, Ocular514/546, ZC(=O)OY, wherein Z is an acyclic radical bonded to the C=O by a carbon and Y is an organic radical bonded to the oxygen by a carbon514/557, Carboxylic acid, percarboxylic acid, or salt thereof (e.g., peracetic acid, etc.)568/8242,6,6-trialkylcyclohexenyls (e.g., vitamin A, etc.)ExaminersPrimary: Page, Thurman K.Assistant: Benston, William E. Jr. Attorney, Agent or FirmInternational ClassA61F 002/00AbstractA tretinoin-mineral oil-petrolatum product in which the ingredients are blended at about 90° C., which product retains its therapeutic activity despite storage at ambient conditions without the need for an antioxidant.Other References
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