Process for the preparation of -bromo-phenylacetic acids
Patent 5036156 Issued on July 30, 1991. Estimated Expiration Date: 
June 19, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
June 19, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.InventorsAssigneeApplicationNo. 540483 filed on 06/19/1990US Classes:562/496, Carboxyl, or salt thereof, not bonded directly to ring546/114, Ring sulfur in the bicyclo ring system562/422Of halo alkyl containing compoundExaminersPrimary: Dentz, BernardAttorney, Agent or FirmInternational ClassesC07C 051/093C07C 051/00 Foreign Application Priority Data1989-09-29 FRAbstractCompounds of formula ##STR1## in which R1 and R2 are hydrogen or halogen, are prepared by reacting an aldehyde of formula: ##STR2## with CHBr3 and KOH in a mixture of an inert solvent and water. Further an ester of compound (I) wherein R1 is H and R2 is 2-Cl is reacted with 4,5,6,7-tetrahydrothieno[3,2-c]pyridine to produce a compound of formula III: ##STR3## which is useful as a medicament.Other References
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