Diagnostic test kit and method for determination of chlamydial or gonococcal antigens using a microporous membrane
October 7, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesPurified antigen to test for Neisseria gonorrheae antibodies Process for preparing hydrophilic polyamide membrane filter media and product Immunoassay for Chlamydia trachomatis antigens Immunoassay for Neisseria gonorrhoeae antigens Particles sensitized with detergent-treated antigen for agglutination immunoassay Use of polyoxyethylene ethers to improve the performance of immunoassays employing peroxidase conjugates Use of phenols and anilines to increase the rate of peroxidase catalyzed oxidation of leuco dyes Determination of chlamydia trachomatis Membrane-supported immunoassays Patent #: 4874691 InventorApplicationNo. 255920 filed on 10/07/1988US Classes:435/7.36, Sexually transmitted disease (e.g., chlamydia, syphilis, gonorrhea, etc.)435/28, Involving peroxidase435/871, Neisseria436/510IMMUNOCHEMICAL PREGNANCY DETERMINATIONExaminersPrimary: Rosen, SamAttorney, Agent or FirmForeign Patent References
International ClassesC12Q 001/00G01N 033/53 AbstractAntigens from chlamydial or gonococcal organisms in specimens containing whole blood, mucus or components thereof can be rapidly and sensitively determined using a polyamide microporous membrane which is coated with a surfactant. This determination is accomplished by contacting extracted antigen with the coated polyamide microporous membrane which is substantially free of any particulate matter. The membrane has an average pore size of from about 1 to about 10 μmeter. Within about 10 minutes of that contacting, antigen bound to the coated membrane is contacted with chlamydial or gonococcal antibody, respectively, so as to form an immunological complex on the membrane. The presence of the complex on the membrane is then determined as a measure of the amount of chlamydial or gonococcal antigen present in the specimen.Other References
Field of SearchIMMUNOCHEMICAL PREGNANCY DETERMINATIONINVOLVING AN INSOLUBLE CARRIER FOR IMMOBILIZING IMMUNOCHEMICALS Carrier is synthetic resin Automated or kit Tube, bottle, or dipstick IMMUNOGENIC CARRIER OR CARRIER PER SE TEST PAPERS PACKAGED DEVICE OR KIT Neisseria Sexually transmitted disease (e.g., chlamydia, syphilis, gonorrhea, etc.) |
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