Methods and articles for treating periodontal disease and bone defects

Patent 5032445 Issued on July 16, 1991. Estimated Expiration Date:

April 5, 2009. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

2748781

2991224

3386440

3589011

3754332

3855638

3863344

3879767

3909852

Process for producing porous products
Patent #: 3953566
Issued on: 04/27/1976
Inventor: Gore

More ...

Inventors

Assignee

W. L. Gore & Associates, Inc.

Application

No. 333289 filed on 04/05/1989

US Classes:

428/158, Foamed or cellular component106/35, Dental428/76, Complete cover or casing428/105, Including grain, strips, or filamentary elements in respective layers or components in angular relation428/113, Fibers428/192, Edge feature428/213, Thickness (relative or absolute)428/318.4, With nonvoid component of specified composition428/343, Adhesive outermost layer428/422, Addition polymer is perhalogenated433/80, Having intra-oral dispensing means433/215, METHOD OR MATERIAL FOR TESTING, TREATING, RESTORING, OR REMOVING NATURAL TEETH604/890.1CONTROLLED RELEASE THERAPEUTIC DEVICE OR SYSTEM

Examiners

Primary: Robinson, Ellis P.
Assistant: Loney, Donald J.

Foreign Patent References

0089782 EP. 08/12/1983
1499912 FR. 03/12/1967
2306672 FR. 05/12/1973
WO90/07308 WO. 07/12/1990
1390445 GB. 04/12/1980
1602932 GB. 11/12/1981

International Classes

A61G 017/02
A61F 013/00
B32B 003/12

Abstract

A method for treatment of periodontal disease is disclosed. The gingival tissue is separated from the tooth surface in an area where periodontal disease is present. A biocompatible, porous material such as expanded polytetrafluoroethylene capable of supporting ingrowth of gingival connective tissue and preventing apical migration of gingival epithelium is placed in a laminar relationship to a portion of the perimeter of the tooth surface. The gingival tissue is repositioned around the tooth and in contact with the porous material, with the porous material positioned between the gingival tissue and the tooth. Articles for the treatment of periodontal disease are also disclosed. One article comprises a first portion which is capable of supporting ingrowth of gingival connective tissue and preventing apical migration of gingival epithelium and a second portion which is impermeable to oral tissues and bacteria.

Other References

J. Periodontol., vol. 51:110 (1980)
Periodontics, vol. 4:71 (1966)
J. Periodontol., vol. 54:29 (1983)
J. Clin. Periodontol. 1974:1:75
J. Periodontal Res. vol. 18:643 (1983)
J. Periodonol. vol. 51:652 (1980)
Prichard, John, "The Roentgenographic Depiction of Periodontal Disease"
Robert Langer & Nikolaos Peppas, "Chemical and Physical Structure of Structure of Polymers as Carriers for Controlled Release of Bioactive Agents: A Review", 4022 Journal of Macromolecular Science Reviews on Macromolecular Chemistry and Physics C23 (1983) No. 1
Murray et al., "Experimental and Clinical Study of New Growth of Bone in a Cavity", American Journal of Surgery vol. 93, Mar. (1957)
Linghorne, "The Sequence of Events in Osteogenesis As Studied in Polyethylene Tubes", Annals New York Academy of Sciences 85:455-460 1960
Melcher et al., "Protection of the Blood Clot in Healing Circumscribed Bone Defects", Journal of Bone and Joint Surgery vol. 44B, No. 2 1962, pp. 424-430
Gongloff et al., "Use of Collagen Tubes for Implantation of Hydroxylapatite", Journal of Maxillofacial Surgery 43:570-573 (1985)
Dahlin et al., "Healing of Bone Defects by Guided Tissue Regeneration", Surgery vol. 81, No. 5 pp. 672-676 (1988)
Aukhil et al., "Guided Tissue Regeneration", Journal Periodontal vol. 57, No. 12 pp. 727-734 (1986)
Magnusson et al., "Connective Tissue Attachment Formation Following Exclusion of Gingival Connective Tissue and Epithelium During Healing", Journal of Periodontal Research vol. 20, pp. 201-208 (1985)
Pitaru et al., "Partial Regneration of Periodontal Tissue Using Collagen barriers", J. Periodontal vol. 59, No. 6, pp. 380-386 (1988)
Velasco et al., "A Study of Autologous Cancellous Bone Particles in Long Bone Discontinuity Defects", Clinical Orthopaedics and Related Research No. 177, pp. 264-273 (1983)
Zander, H. A., Polson, A. M. and Heiil, C. D.: Goals of Periodontal Therapy, J. Periodontal 47:261, 1976
Melcher, A. H.: On the Repair Potential of Periodontal Tissues, J. Periodontal 47:256, 1976
McCulloch, C. A. G., and Melcher, A. H.: Cell Density and Cell Generation in the Periodontal Ligament of Mice, Am. J. Anat. 167:43, 1983
Aukil, I., Petterson, E. and Suggs, C.: Periodontal Wound Healing in the Absence of Periodontal Ligament Cells, J. Periodontal 58:71, 1987
Nyman, S, Gottlow, J., Karring, T. and Lindhe, J.: the Regenerative Potential of the Periodontal Ligament, An Experimental Study in the Monkey, J. Clin. Periodontal 9:257, 1982
Gottlow, J., Nyman, S., Karring, T. and Lindhe, J.: New Attachment Formation as the Result of Controlled Tissue Regeneration, J. Clin. Periodontal 11:494, 1984
Caton, J. G., Defuria, E. L., Polson, A. M. and Nyman, S.: Periodontal Regeneration Via Selective Cell Repopulation, J. Periodontal 58:546, 1987
Quiones, C. R., Caton, J. G., Mota, L. F., Polson, A. M. and Wagener, C. J. Evaluation of a Synthetic Biodegradable barrier to Facilitate Guided Tissue Regeneration, J. Dent. Res. 69: Special Issue, 1990, Abstract #1336
Caton, J. G., Frantz, B, Greenstein, G., Hoffman, P., Polson, A. M., and Zappa, O: Synthetic Biodegradable Barrier for Regeneration in Human Periodontal Defects, J. Dent. Res. 69: Special Issue, 1990, Abstract #133