Pharmaceutical microemulsions
Patent 5023271 Issued on June 11, 1991. Estimated Expiration Date: 
June 11, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
June 11, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3384545 Parenteral preparations Pharmaceutical compositions for parenteral or local administration Pharmaceutical compositions for parenteral or local administration Lipid membrane drug delivery Patent #: 4377567 InventorsAssigneeApplicationNo. 765359 filed on 08/13/1985US Classes:514/458, Tocopherols (e.g., vitamin E, etc.)514/168, With a vitamin type active ingredient514/546, ZC(=O)OY, wherein Z is an acyclic radical bonded to the C=O by a carbon and Y is an organic radical bonded to the oxygen by a carbon514/547, Compound contains two or more C(=O)O groups514/589, Nitro or nitroso bonded directly to amino nitrogen (e.g., nitramine, nitrosamine, nitro-urea, etc.)514/681, Bicyclo514/725, Vitamin A compound or derivative514/788Nitrogen containingExaminersPrimary: Goldberg, Jerome D.Assistant: Henley, III, Raymond Attorney, Agent or FirmForeign Patent References
International ClassesA61K 031/355A61K 031/595 A61K 031/07 A61K 031/225 AbstractA method for parenteral administration of fat-soluble pharmaceuticals and vitamins using microemulsions is disclosed. The microemulsions are comprised of a naturally occurring amphipatic substance and a hydrophobic lipid along with the active ingredient, are size selected for 300-1000 Å pseudomicelles, and permit safe intravenous injection of the active ingredient. Levels of the active ingredient in the various lipoprotein fractions of serum appear to mimic the natural distribution of the administered drug if taken orally.Other References
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