Method of traeting malaria with cyproheptadine derivatives
Patent 5021426 Issued on June 4, 1991. Estimated Expiration Date: 
February 26, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
February 26, 2010. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3014911 Process for preparing aryl trifluoromethylsulfides Trifluoromethylthio (and sulfonyl) derivatives of cyproheptadine analogs Antipsychotic levorotatory enantiomers of 3-halocyproheptadines, analogs and derivatives Arloxyphenylpropylamines Patent #: 4314081 InventorsAssigneeApplicationNo. 484774 filed on 02/26/1990US Classes:514/313, Nitrogen, other than as nitro or nitroso, attached directly to the six membered hetero ring by nonionic bonding514/314, Additional hetero ring attached directly or indirectly to the quinoline ring system by nonionic bonding514/318, The additional ring is a six-membered hetero ring consisting of one nitrogen and five carbon atoms514/325, Polycyclo ring system is tricyclo-carbocyclic514/895MALARIAExaminersPrimary: Hollrah, Glennon H.Assistant: Hollinden, Gary E. Attorney, Agent or FirmInternational ClassesA61K 031/47A61K 031/445 AbstractVarious 3-substituted cyproheptadine derivatives are useful in the treatment of infection by Plasmodium falciparum and in the treatment of malaria either as compounds, pharmaceutically acceptable salts, or pharmaceutical composition ingredients in combination with antimalarial agents or compounds. Methods of treating malaria and methods of treating infection by Plasmodium falciparum are also described.Other References
Field of SearchThe additional ring is a six-membered hetero ring consisting of one nitrogen and five carbon atomsPolycyclo ring system is tricyclo-carbocyclic Ring nitrogen in the additional hetero ring (e.g., oxazole, etc.) Nitrogen attached directly to the six-membered hetero ring by nonionic bonding Nitrogen, other than as nitro or nitroso, attached directly to the six membered hetero ring by nonionic bonding Additional hetero ring attached directly or indirectly to the quinoline ring system by nonionic bonding MALARIA | |
