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US Patent 5011694 - Pharmaceutical dosage unit forms with delayed release

US Patent Issued on April 30, 1991
Estimated Patent Expiration Date: Icon_subject August 1, 2009Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
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Abstract

Improved delayed release pharmaceutical dosage unit forms such as tablets are obtained by exposing a matrix of a compressed mixture of active pharmaceutical ingredient and of a polyacrylic ester polymer or a vinyl ester polymer insoluble in body fluids at the point of release to vapors of a lower alcohol.

Other References

  • Journal of Pharmaceutical Sciences, 60 (2), 212-215 (1971), Farhadieh et al., "Drug Release from Methyl-Acrylate-Methyl Methacrylate Copolymer Matrix II: Control of Release Rate by Exposure to Acetone Vapor

Inventors

Application

No. 388120 filed on 08/01/1989

US Classes:

424/464, Tablets, lozenges, or pills424/462, Containing solid synthetic polymers424/468, Sustained or differential release type424/473, With porous, perforated, apertured, or sieved layer (e.g., dialyzing layer, microporous layer, etc.)427/336Swelling agent or solvent applied to treat coating

Field of Search

424/464, Tablets, lozenges, or pills424/462, Containing solid synthetic polymers424/468, Sustained or differential release type424/473, With porous, perforated, apertured, or sieved layer (e.g., dialyzing layer, microporous layer, etc.)424/469, Discrete particles in supporting matrix264/4.6, Solid-walled microcapsule formed by physically removing a constituent (e.g., evaporation, extraction, etc.)264/4.33, Microcapsule wall derived from synthetic polymer427/336Swelling agent or solvent applied to treat coating

Examiners

Primary: Page, Thurman K.
Assistant: Phelan, D. Gabrielle

Attorney, Agent or Firm

US Patent References

2987445, 3087860, 3148124, 4013820, Universally useable tableting ingredients
Issued on: 03/22/1977
Inventor: Farhadieh ,   et al.
4851233, Sustained release formulations
Issued on: 07/25/1989
Inventor: Khan ,   et al.
4853249Method of preparing sustained-release pharmaceutical/preparation
Issued on: 08/01/1989
Inventor: Takashima ,   et al.

Foreign Patent References

  • 2187643 GB. 09/21/1987

International Class

A61K 009/20

Foreign Application Priority Data

1988-08-11 DE

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