Sustained pulsewise release pharmaceutical preparation
Patent 5011692 Issued on April 30, 1991. Estimated Expiration Date: 
April 30, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
April 30, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesSystem with microporous reservoir having surface for diffusional delivery of agent Process for producing a multi-layered slow release composite Osmotic drug delivery system Rate-controlled drug release system Active agent dispenser Osmotic capsule Disc-like sustained release formulation Patent #: 4663147 InventorsAssigneeApplicationNo. 946158 filed on 12/23/1986US Classes:424/426, Errodable, resorbable, or dissolving424/425, Diffusion barrier is matrix424/484, Matrices424/485, Natural gums, resin or latex424/486Synthetic polymerExaminersPrimary: Lovering, Richard D.Assistant: Covert, John M. Attorney, Agent or FirmForeign Patent References
International ClassA61F 002/00Foreign Application Priority Data1985-12-28 JPAbstractThe invention relates to sustained pulsewise release pharmaceutical preparation which comprices drug-containing polymeric material layers (layers A) and polymeric material layers containing the drug in question only in a slight amount or free of the drug (layers B) disposed alternatingly, with the whole surface extending in the direction perpendicular to the layer plane being coated with a polymeric material which is insoluble in water or scarcely soluble in water (polymeric material C).This pharmaceutical preparation of this invention is designed so that active ingredients which should desirably be released pulsewise can be released therefrom in a pulse-like and clinically significant manner and thereby the pharmacological effects of said active ingredients can be maintained for a prolonged period of time.Other References
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