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US Patent 5009892 - Rapid miosis with control of intraocular pressure
US Patent Issued on April 23, 1991
Estimated Patent Expiration Date:
March 3, 2009Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
Estimated Patent Expiration Date:
March 3, 2009Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.AbstractQuick miosis with 24 hour control of intraocular pressure of patients undergoing extracapsular cataract extraction surgery is achieved by applying to the eyes of the patient during surgery acetylcholine as a first miotic agent and carbachol as a second miotic agent. Acetylcholine provides quick miosis while carbachol enhances the miotic effect while providing post-surgery control of intraocular pressure. The two miotic agents can be dissolved in a common saline carrier. The two agents can be combined in a unit dosage package by disposing acetylcholine in powder form in a first compartment and a solution of carbachol in a second compartment. The combined miotic agent of the invention is especially useful when substances which raise IOP such as viscoelastic agents are used during ocular surgery and/or with sensitive patients who enter the surgery with elevated pressure such as those suffering from glaucoma. | InventorApplicationNo. 318753 filed on 03/03/1989US Classes:424/422, Implant or insert424/423, Surgical implant or material424/427, Ocular424/428Bioerrodable, resorbable, or dissolvingField of Search424/422, Implant or insert424/423, Surgical implant or material424/427, Ocular424/428Bioerrodable, resorbable, or dissolvingExaminersPrimary: Page, Thurman K.Attorney, Agent or FirmUS Patent References3870791, 4405627, Diphenylpropylamino-pyridine compounds useful as medicinesIssued on: 09/20/1983 Inventor: Masi , et al.4459309, Compositions and methods of lowering intraocular pressure in the hypertensive mammalian eye Issued on: 07/10/1984 Inventor: Chiou4490379, Method of reducing intraocular pressure and treating glaucoma using corynanthine Issued on: 12/25/1984 Inventor: Podos , et al.4853224Biodegradable ocular implants Issued on: 08/01/1989 Inventor: Wong International ClassA61K 009/00 |
