Patent 5001149 Issued on March 19, 1991. Estimated Expiration Date: March 19, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
Derivatives of azadirachtin are described which should facilitate their synthesis and provide greater stability than their naturally-occurring counterpart. The derivative 2',3',22,-23-tetraydroanzadirachtin is also described, that derivative retaining full activity and having enhanced stability. Insecticidal and antifeedant compositions including these compounds also described.
Other References
Kubo et al., "Insect Ecdysis Inhibitors", in Natural Resistance of Plants to Pests, pp. 206-219, ACS Sympsosium Series 296 (1986)
Morgan, "Strategy in the Isolation of Insect Control Substances from Plants, " Proc. 1st Int. Neem Conf., pp. 43-52 (Rottach-Egerm 1980), (Schmutterer et al., Eds. 1982)
Butterworth et. at., J. Chem Soc. (Chem. Commun) pp. 23-24 (1968)
Qadri, et al., Indian J. Exp. Biol. 16: 1141-1143 (1978)
Sieber, et al., J. Insect Physiol. 29: 523-527 (1983)
Kubo et al., Agric. Biol. Chem 46 (7): 1951-1953 (1982)
Litchfield et al., J. Pharm & Exp Therapeutics 96: 99-113 (1949)
Yamasaki et al., J. Chromatog. 356: 220-226 (1986)
Truman et al., Nature 291: 70-71 (1981)
Truman, Amer. Zool. 21: 655-661 (1981)
Taylor et al., Abstract No. 177, Intnl. Res. Cong. on Nat. Prod., Chapel Hill, N.C. (Jul. 1985)
Broughton et al., J. Chem. Soc. (Chem. Commun.) 47, (1986)
Bokel et al., J. Chem Soc. (Chem. Commun.) 523 (1986)
Kubo et al., "Plant Resistance to Insects", pp. 329-346, ACS Symposium Series 208, (1983)
Lee et al., J. Liq. Chromatog, 10(6): 1151-1163 (1987