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US Patent 5001053 - Method and apparatus for measuring the product of an antigen-antibody reaction

US Patent Issued on March 19, 1991
Estimated Patent Expiration Date: Icon_subject September 12, 2008Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
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Abstract

A method and an apparatus for detecting antigen-antibody reaction are disclosed in which a predetermined antigen or antibody is made to attach to the surface of an oscillator and the oscillator is immersed in the specimen blood so as to cause antigen-antibody reaction on the surface thereof. The oscillator is then made to oscillate and the amount of antibody or antigen attaching to the surface of the oscillator is determined in accordance with the data concerning the oscillation of the oscillator.

Other References

  • Patent Abstracts of Japan, 62-150148, Yoshikawa et al., Abs. vol. 11, No. 383; Published 12/15/198

Inventors

Assignee

Application

No. 243296 filed on 09/12/1988

US Classes:

435/7.1, Involving antigen-antibody binding, specific binding protein assay or specific ligand-receptor binding assay422/68.1, Means for analyzing liquid or solid sample422/82.01, Measuring electrical property435/4, MEASURING OR TESTING PROCESS INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITION OR TEST STRIP THEREFORE; PROCESSES OF FORMING SUCH COMPOSITION OR TEST STRIP435/810, PACKAGED DEVICE OR KIT436/501, BIOSPECIFIC LIGAND BINDING ASSAY436/510, IMMUNOCHEMICAL PREGNANCY DETERMINATION436/518, INVOLVING AN INSOLUBLE CARRIER FOR IMMOBILIZING IMMUNOCHEMICALS436/806ELECTRICAL PROPERTY OR MAGNETIC PROPERTY

Field of Search

435/4, MEASURING OR TESTING PROCESS INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITION OR TEST STRIP THEREFORE; PROCESSES OF FORMING SUCH COMPOSITION OR TEST STRIP436/501, BIOSPECIFIC LIGAND BINDING ASSAY436/518, INVOLVING AN INSOLUBLE CARRIER FOR IMMOBILIZING IMMUNOCHEMICALS436/806, ELECTRICAL PROPERTY OR MAGNETIC PROPERTY422/68.1, Means for analyzing liquid or solid sample422/82.01Measuring electrical property

Examiners

Primary: Kepplinger, Esther M.
Assistant: Spiegel, Carol A.

Attorney, Agent or Firm

US Patent References

4236893, Method for the assay of classes of antigen-specific antibodies
Issued on: 12/02/1980
Inventor: Rice
4242096, Immunoassay for antigens
Issued on: 12/30/1980
Inventor: Oliveira ,   et al.
4537861Apparatus and method for homogeneous immunoassay
Issued on: 08/27/1985
Inventor: Elings ,   et al.

Foreign Patent References

  • 8002201 WO. 10/22/1980

International Class

G01N 033/543

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