Compositions for treating tobacco withdrawal symptoms and methods for their use
Patent 4999382 Issued on March 12, 1991. Estimated Expiration Date: October 26, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
Compositions useful in the treatment of disturbances of appetite, disturbances of mood, or both, nicotine withdrawal associated as well as experienced by individuals after discontinuing tobacco use as methods of use therefor. The compositions include serotoninergic drugs, such as d-fenfluramine and fluoxetine.
Other References
M. E. Benwell et al., Journal of Neurochemistry, 50(4): 1243-1247 (1988)
D. K. Hatsukami et al., Psychopharmacology, 84: 231-236 (1984)
N. G. Schneider and M. E. Jarvik, Psychopharmacology, 82: 143-144 (1984)
N. E. Grunberg, Addictive Behaviors, 7(4): 317-331 (1982)
N. E. Grunberg et al., Psychopharmacology, 87: 198-203 (1985)
E. Wong, Can. Med. Assoc, J., 107: 727 (1972)
M. A. Jacobs et al., Psychosom. Med., 33: 545-556
B. Luban-Plozza, Munch. Med. Wochenschr., 112: 2322-2327 (1970)
N. B. Edwards et al., Psychosomatics, 29: 203-206 (1988)
E. M. Sellers et al., J. Clin. Psychopharmacol., 7: 417-420 (1987)
G. L. S. Pawan et al., Br. J. Pharmacol., 41: 416P-417P (1971)
P. Turner et al., Int. J. Obesity, 6: 411-415 (1982)