Novel pharmaceutical compositions for topical application with systemic action
Patent 4999379 Issued on March 12, 1991. Estimated Expiration Date: 
May 5, 2009. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
May 5, 2009. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3558690 Vehicle composition containing 1-substituted azacycloheptan-2-ones Penetration enhancers for transdermal drug delivery of systemic agents Percutaneous absorption preparation Patent #: 4873081 InventorAssigneeApplicationNo. 348325 filed on 05/05/1989US Classes:514/567, Benzene ring nonionically bonded514/825, ARTHRITIS514/916PYRETICExaminersPrimary: Friedman, Stanley J.Assistant: Fay, Zohreh Attorney, Agent or FirmForeign Patent References
International ClassA61K 031/195Foreign Application Priority Data1986-06-27 CHAbstractThere are disclosed novel pharmaceutical compositions which comprise diclofenac or a salt thereof, a penetration agent such as 1-n-dodecylazacycloheptan-2-one or dimethyllauroylamide and, as vehicle, a mineral oil. These compositions have excellent skin penetration properties and can therefore be used in transdermal therapeutic systems (TTS) as drug reservoir. | |
