Enzymatically amplified piezoelectric specific binding assay
Patent 4999284 Issued on March 12, 1991. Estimated Expiration Date: 
April 6, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
April 6, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesAlkaline phosphatase isoenzyme determination Process and apparatus for electrolysis of hydrochloric acid Analytical device having semiconductive organic polymeric element associated with analyte-binding substance Electrochemical enzymic assay procedures Patent #: 4830959 InventorsAssigneeApplicationNo. 178366 filed on 04/06/1988US Classes:435/4, MEASURING OR TESTING PROCESS INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITION OR TEST STRIP THEREFORE; PROCESSES OF FORMING SUCH COMPOSITION OR TEST STRIP204/403.1, Enzyme included in apparatus205/778, And using semipermeable membrane435/6, Involving nucleic acid435/7.8, Involving nonmembrane bound receptor binding or protein binding other than antigen-antibody binding435/7.92, Heterogeneous or solid phase assay system (e.g., ELISA, etc.)435/7.94, Sandwich assay435/21, Involving phosphatase435/28, Involving peroxidase435/173.1, TREATMENT OF MICRO-ORGANISMS OR ENZYMES WITH ELECTRICAL OR WAVE ENERGY (E.G., MAGNETISM, SONIC WAVES, ETC.)435/817, ENZYME OR MICROBE ELECTRODE436/501, BIOSPECIFIC LIGAND BINDING ASSAY436/531, Carrier is synthetic resin436/532, Antigen or antibody attached to a carrier via bridging agent436/537, Signal modification or steric inhibition436/544, Producing labeled antigens436/547, INVOLVING PRODUCTION OR TREATMENT OF ANTIBODY436/806ELECTRICAL PROPERTY OR MAGNETIC PROPERTYExaminersPrimary: Wax, Robert A.Assistant: Beisner, William H. Foreign Patent References
International ClassesC12Q 001/00G01N 033/53 C12N 013/00 AbstractA quartz crystal microbalance assay in which the binding of analyte to a surface on or near a quartz crystal microbalance (QCM) is detected by a conjugate which comprises an enzyme capable of catalyzing the conversion of a substrate to a product capable of accummulating on or reacting with a surface of the QCM leading to a mass change and, hence, a change in resonant frequency.Other References
Field of SearchMEASURING OR TESTING PROCESS INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITION OR TEST STRIP THEREFORE; PROCESSES OF FORMING SUCH COMPOSITION OR TEST STRIPInvolving nucleic acid Involving phosphatase Involving peroxidase ENZYME OR MICROBE ELECTRODE BIOSPECIFIC LIGAND BINDING ASSAY Carrier is synthetic resin Antigen or antibody attached to a carrier via bridging agent Signal modification or steric inhibition Producing labeled antigens INVOLVING PRODUCTION OR TREATMENT OF ANTIBODY ELECTRICAL PROPERTY OR MAGNETIC PROPERTY |
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