Sustained release drug-resin complexes
Patent 4996047 Issued on February 26, 1991. Estimated Expiration Date: 
November 2, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
November 2, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 2990332 3138525 3155590 3499960 3594470 Stabilized polycarbonate compositions Prolonged release pharmaceutical preparations Process for preparing pharmaceutically active compound-containing microcapsules Process for preparing ethylcellulose microcapsules Resinate sustained release dextromethorphan composition InventorsAssigneeApplicationNo. 265910 filed on 11/02/1988US Classes:424/486, Synthetic polymer424/78.1, Ion exchange resin424/78.13, Oxygen or sulfur heterocycle424/78.14, Nitrogen heterocycle424/78.15, Plural nitrogen heteroatoms or rings424/483, Ion-exchange resins424/484, Matrices424/490, Coated (e.g., microcapsules)424/494, Cellulose derivatives514/781, Cellulose or derivative514/964SUSTAINED OR DIFFERENTIAL RELEASE TYPEExaminersPrimary: Brown, Johnnie R.Assistant: Pili-Curtis, Carmen Attorney, Agent or FirmForeign Patent References
International ClassesA61K 031/74A61K 009/14 A61K 009/52 AbstractDisclosed are oral pharmaceutical preparations which comprise a pharmacologically active drug bound to small particles of an ion-exchange resin to provide a drug-resin complex having a drug content above a specified value. The drug-resin complex is subsequently coated with a water-permeable diffusion barrier coating that is insoluble in gastrointestinal fluids thereby providing a controllable sustained release of drug under conditions encountered in the gastrointestinal tract.Other References
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