U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Multi-layer granule

Patent 4994279 Issued on February 19, 1991. Estimated Expiration Date: Icon_subject January 26, 2009. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

T861008

2921883

2991226

3577512

3879511

Nitrofurantoin sustained release tablet
Patent #: 4122157
Issued on: 10/24/1978
Inventor: Huber

Sustained release pharmaceutical composition
Patent #: 4138475
Issued on: 02/06/1979
Inventor: McAinsh ,   et al.

Prolonged-release pharmaceutical compositions for oral administration, their methods of making and use
Patent #: 4155993
Issued on: 05/22/1979
Inventor: Belleville ,   et al.

Theophylline sustained release granule
Patent #: 4261970
Issued on: 04/14/1981
Inventor: Ogawa ,   et al.

Sustained release pharmaceutical compositions
Patent #: 4309405
Issued on: 01/05/1982
Inventor: Guley ,   et al.

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Inventors

Application

No. 302646 filed on 01/26/1989

US Classes:

424/494, Cellulose derivatives424/490, Coated (e.g., microcapsules)424/493, Containing polysaccharides (e.g., sugars)424/496, Containing natural gums/resins424/498Containing waxes, higher fatty acids, higher fatty alcohols, or derivatives thereof

Examiners

Primary: Page, Thurman K.

Attorney, Agent or Firm

Foreign Patent References

  • 0074584 EP. 03/13/1983
  • 0220670 EP. 05/13/1987
  • 2721603 DE. 05/13/1976
  • 3403329 DE 08/13/1985
  • 2404029 FR. 04/13/1979
  • 0935602 GB 08/13/1963

International Class

A61K 009/50

Foreign Application Priority Data

1988-02-03 JP

Abstract

A multi-layered granule comprises an inner, slow-releasing layer, an outer, rapid-releasing layer and an intermediate layer provided between said slow-releasing layer and said rapid-releasing layer which intermediate layer comprises a hardened oil and hydroxypropyl cellulose or methyl cellulose.

Other References

  • "Stearate" Definition: Hackh's Chemical Dictionary--4th Edition, Ed.--Julius Gran
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