U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Chlorhexidine complex

Patent 4980150 Issued on December 25, 1990. Estimated Expiration Date: Icon_subject April 27, 2009. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3842168

Treatment of teeth
Patent #: 3956480
Issued on: 05/11/1976
Inventor: Dichter ,   et al.

Polymeric diffusion matrix containing phenylpropanolamine
Patent #: 4289749
Issued on: 09/15/1981
Inventor: Keith ,   et al.

Salt of chlorhexidine
Patent #: 4393219
Issued on: 07/12/1983
Inventor: Inoue ,   et al.

Pharmaceutical preparation for remedy of periodontal disease and process for production thereof
Patent #: 4569837
Issued on: 02/11/1986
Inventor: Suzuki ,   et al.

Chlorhexidine salts and compositions of same
Patent #: 4666896
Issued on: 05/19/1987
Inventor: Warner, Jr. ,   et al.

Dentifrice gel
Patent #: 4857303
Issued on: 08/15/1989
Inventor: Grollier

Fungicidal and bactericidal method Patent #: 4877617
Issued on: 10/31/1989
Inventor: Namikoshi, et al.

Inventor

Assignee

Application

No. 344257 filed on 04/27/1989

US Classes:

424/49, DENTIFRICES (INCLUDES MOUTH WASH)424/78.07, Anti-infective514/54, Polysaccharide514/779, Algin or derivative514/781, Cellulose or derivative514/901, Mouthwash536/3Algin or derivative

Examiners

Primary: Griffin, Ronald W.

Attorney, Agent or Firm

International Class

A61K 007/16

Abstract

A chlorhexidine complex is prepared by complexing chlorhexidine (a divalent, cationic antiseptic) with an anionic polymer such as algin or carboxymethylcellulose. The complex is insoluble but can be granulated or crushed to a fine powder. In powdered form the complex forms stable aqueous dispersions. The chlorhexidine complex is suitable for inclusion in oral hygiene compositions such as dentrifrices, and in other antibacterial compositions such as opthalmic under-eye-lid treatment capsules topical preparations and ocular solutions.

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