Tissue-affinitive collagen for osteogenesis and method of producing the same
Patent 4975527 Issued on December 4, 1990. Estimated Expiration Date: 
June 28, 2009. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
June 28, 2009. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesSterile surgical collagen product Artificial bone Bone graft material for osseous defects and method of making same Inductive collagen based bone repair preparations Patent #: 4563350 InventorsApplicationNo. 372115 filed on 06/28/1989US Classes:530/356, Collagen435/68.1, Enzymatic production of a protein or polypeptide (e.g., enzymatic hydrolysis, etc.)514/21, Produced by or extracted from animal tissue514/801, COLLAGEN, GELATIN OR DERIVATIVES THEREOF530/840Bones; tendons; teeth; cartilageExaminersPrimary: Nutter, Nathan M.Attorney, Agent or FirmForeign Patent References
International ClassesA61K 037/12C07K 003/00 C07K 013/00 Foreign Application Priority Data1985-06-21 JPAbstractA good tissue-affinity and lack of antigenicity are required for the collagen used as the carrier of BMP. Conventional collagens have these properties only insufficiently. When the tyrosine content is below 2 residues/1000 residues, then the above properties of such collagens are good. Moreover, collagens excelling in the above properties can be readily obtained by using proteolytic enzymes.Other References
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