Patent References 2410417 Formulations providing three distinct releases Patent #: 4794001 InventorsAssigneeApplicationNo. 255199 filed on 08/25/1988US Classes:424/494, Cellulose derivatives424/458, Containing discrete coated particles pellets, granules, or beads424/459, Organic coatings424/462, Containing solid synthetic polymers424/468, Sustained or differential release type424/480, Cellulose or derivative424/482, Containing solid synthetic polymers424/497Containing solid synthetic polymersExaminersPrimary: Page, Thurman K.Attorney, Agent or FirmForeign Patent References
International ClassA61K 009/58Foreign Application Priority Data1987-12-23 WOAbstractSlow-releasing granules which are characterized by coating the quick-releasing granules which comprise an active ingredient, polyvinyl pyrrolidone polymer and a disintegrator where the polymer distributes in high concentration on the surface area of the granules, with a polyacid enteric material to form a complex between the polyvinyl pyrrolidone polymer and the polyacid, and long lasting mixed granules which comprise the quick-releasing granules and the slow-releasing granules, thus showing increased bioavailability of the active ingredient and high stability sustained for a long period of time. | |