U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Slow-releasing granules and long acting mixed granules comprising the same

Patent 4971805 Issued on November 20, 1990. Estimated Expiration Date: Icon_subject August 25, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

2410417

Formulations providing three distinct releases Patent #: 4794001
Issued on: 12/27/1988
Inventor: Mehta ,   et al.

Inventors

Assignee

Application

No. 255199 filed on 08/25/1988

US Classes:

424/494, Cellulose derivatives424/458, Containing discrete coated particles pellets, granules, or beads424/459, Organic coatings424/462, Containing solid synthetic polymers424/468, Sustained or differential release type424/480, Cellulose or derivative424/482, Containing solid synthetic polymers424/497Containing solid synthetic polymers

Examiners

Primary: Page, Thurman K.

Attorney, Agent or Firm

Foreign Patent References

  • 0077956 EP. 10/13/1982
  • 0103991 EP 03/13/1984
  • 0148811 EP. 01/13/1985
  • 0210540 EP. 07/13/1986
  • 2272639 FR. 12/13/1975
  • 2331375 FR. 06/13/1977
  • 1464192 GB. 02/13/1975
  • 1560841 GB. 02/13/1976
  • 2098867 GB 12/13/1982
  • 2159715 GB 12/13/1985

International Class

A61K 009/58

Foreign Application Priority Data

1987-12-23 WO

Abstract

Slow-releasing granules which are characterized by coating the quick-releasing granules which comprise an active ingredient, polyvinyl pyrrolidone polymer and a disintegrator where the polymer distributes in high concentration on the surface area of the granules, with a polyacid enteric material to form a complex between the polyvinyl pyrrolidone polymer and the polyacid, and long lasting mixed granules which comprise the quick-releasing granules and the slow-releasing granules, thus showing increased bioavailability of the active ingredient and high stability sustained for a long period of time.

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