U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Biodegradable matrix and methods for producing same

Patent 4970298 Issued on November 13, 1990. Estimated Expiration Date: Icon_subject November 13, 2007. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Method for making collagen sponge
Patent #: 4193813
Issued on: 03/18/1980
Inventor: Chvapil

Macromolecular biologically active collagen articles
Patent #: 4440680
Issued on: 04/03/1984
Inventor: Cioca

Method for preserving porosity in porous materials Patent #: 4522753
Issued on: 06/11/1985
Inventor: Yannas ,   et al.

Inventors

Assignee

Application

No. 875827 filed on 06/18/1986

US Classes:

530/356, Collagen424/94.64, Serene proteinases (3.4.21) (e.g., trypsin, chymotrypsin, plasmin, thrombin, elastase, kallikrein, fibrinolysin, streptokinease, etc.)424/485, Natural gums, resin or latex523/105, Nonmedicated composition specifically intended for contact with living animal tissue or process of preparing; other than apparel523/111Compositions for use in tape adhesives, binder or impregnate for a body fluid adsorbent device, e.g., a surgical adhesive tape, etc.

Examiners

Primary: Kight, John
Assistant: Nutter, Nathan M.

Attorney, Agent or Firm

International Classes

A23J 001/10
C08H 001/06

Abstract

This invention relates to a biodegradable collagen matrix having a pore size and morphology which enhances the healing of a wound. It further relates to a process for preparing the matrix. One embodiment of the invention comprises a biodegradable matrix which comprises collagen, hyaluronic acid and fibronectin. Other embodiments include a process which comprises freeze drying a dispersion containing collagen, crosslinking the collagen via two crosslinking steps and freeze drying the crosslinked matrix.

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