Drug delivery compositions and methods
December 15, 2007. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 2897119 2913342 3190837 Lipid encapsulated hemoglobin cells Intravascularly-administrable, magnetically-localizable biodegradable carrier Magnetically-localizable, biodegradable lipid microspheres Method of incorporating water-soluble heat-sensitive therapeutic agents in albumin microspheres Process for prolonging retention of emulsion particles in the bloodstream Synthetic phosphatidyl cholines useful in forming liposomes Drug administration InventorAssigneeApplicationNo. 130550 filed on 12/15/1987US Classes:424/485, Natural gums, resin or latex128/200.16, Ultrasonic264/4.1, Liquid encapsulation utilizing an emulsion or dispersion to form a solid-walled microcapsule (includes liposome)264/4.32, Microcapsule wall containing two or more layers264/4.7, Solid-walled microcapsule formed by in situ polymerization424/455, Containing emulsions, dispersions, or solutions424/460, Containing proteins or derivatives thereof (e.g., gelatin, etc.)424/484, Matrices424/486, Synthetic polymer428/402.2, Microcapsule with fluid core (includes liposome)514/832, BLOOD SUBSTITUTE514/833, BLOOD PLASMA EXTENDER514/911, Bulking agent514/944, GEL514/947, Topical application514/959, BREATHING GASES514/963, Microcapsule-sustained or differential release514/965, Discrete particles in supporting matrix514/975, CHARACTERIZED BY THE DESIGNATED SURFACTANT USED604/892.1Osmotic or diffusion pumped device or systemExaminersPrimary: Lovering, Richard D.Attorney, Agent or FirmInternational ClassesA61K 009/22A61K 009/64 A61K 009/66 B01J 013/02 AbstractDrug delivery compositions yeild new and unexpected degrees of stabilization, solubilization and delivery of incorporated medicaments, drugs, or other physiologically-active compounds. The compositions enable administration of drugs and other medically useful compounds via a variety of routes. More particularly, a drug delivery system or composition including one or more monomeric or polymerized surface active agents allows for rapid dissolution and smooth liberation of any desired incorporated drug or combinations, and the method of preparing the drug composition. In one embodiment, the physiologically-active compound is encapsulated by a coacervate-derived film, and the finished product is suitable for transmucosal administration. Other formulations of this invention may be administered via inhalation, oral, parenteral and by transdermal and transmucosal routes.Other References
Field of SearchLiquid encapsulation utilizing an emulsion or dispersion to form a solid-walled microcapsule (includes liposome)Microcapsule wall containing two or more layers Solid-walled microcapsule formed by in situ polymerization Microcapsule with fluid core (includes liposome) Lecithins BLOOD SUBSTITUTE BLOOD PLASMA EXTENDER Bulking agent Microcapsule-sustained or differential release GEL BREATHING GASES Topical application Discrete particles in supporting matrix CHARACTERIZED BY THE DESIGNATED SURFACTANT USED Ultrasonic Osmotic or diffusion pumped device or system Natural gums, resin or latex Synthetic polymer Containing emulsions, dispersions, or solutions Containing proteins or derivatives thereof (e.g., gelatin, etc.) Matrices | |
