Stabilized aqueous solutions of pharmaceutically acceptable salts of ortho-(2,6-dichlorophenyl)-aminophenylacetic acid for opthalmic use
April 5, 2009. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3558690 3652762 Surgical skin scrub Ophthalmic suspensions Method of treating vascularization of the eye with Flurbiprofen Analgesic potentiation Antiphlogistic pharmaceutical compositions and method of use Stabilized parenterally administrable solutions Pharmaceutical compositions Ophthalmic formulations of 5-fluoro-2-methyl-1-(p-methylthiobenzylidene)-3-indenylacetic acid InventorAssigneeApplicationNo. 333772 filed on 04/05/1989US Classes:514/567, Benzene ring nonionically bonded514/912, OPHTHALMIC514/914, Inflammation514/970CONTAINING DESIGNATED INGREDIENT TO STABILIZE AN ACTIVE INGREDIENTExaminersPrimary: Hoke, Veronica P.Attorney, Agent or FirmForeign Patent References
International ClassA61K 031/195AbstractStorage stable aqueous ophthalmic, substantially isotonic solutions of pharmaceutically acceptable salts of ortho-(2,6-dichlorophenyl) aminophenylacetic acid, and having a pH of about 7.0 to about 7.8, comprising per ml solution:(a) about 0.1 to about 5.0 mg of a pharmaceutically acceptable salt of ortho-(2,6-dichlorophenyl)aminophenylacetic acid;(b) about 0.1 to about 10 mg of a pharmaceutically acceptable salt of ethylenediamine tetraacetic acid;(c) about 0.5 to about 200 mg of a pharmaceutically acceptable solubilizer;(d) about 0.01 to about 5.0 mg of a pharmaceutically acceptable bacteriostat; and(e) the remainder water,and the use of such solutions, by topical administration to the eye of a warm blood mammal, for the control or treatment of ocular inflammation. | |
