Therapeutic valine esters of acyclovir and pharmaceutically acceptable salts thereof
August 4, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesMethods and compositions for treating viral infections and guanine acyclic nucleosides Purine derivatives Purine derivatives Method of imparting immunomodulating, antiviral or antitumor activity Derivatives of 9-(2-hydroxyethoxymethyl) guanine Compounds endowed with immunomodulating activity Antiviral compound use Method for using purine derivatives Patent #: 4745119 InventorAssigneeApplicationNo. 228377 filed on 08/04/1988US Classes:514/263.38, Chalcogen attached indirectly to the 9- position of the purine ring system by acyclic nonionic bonding544/276Nitrogen attached directly or indirectly to the purine ring system by nonionic bondingExaminersPrimary: Rivers, Diana G.Attorney, Agent or FirmForeign Patent References
International ClassesA61K 031/52C07D 473/16 Foreign Application Priority Data1987-08-15 GBAbstractThe present invention relates to certain amino acid exters of the purine nucleoside acyclovir, pharmaceutically acceptable salts thereof and their use in the treatment of herpes virus infections. The invention also includes pharmaceutical formulations and processes for the preparation of such compounds. |
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